Breakthrough Achievement: Ivory Tower’s LPU & Kashmir University Pioneering Hope in Colorectal Cancer Research
In a significant stride for cancer research, scientists from Lovely Professional University (LPU) and the University of Kashmir have developed a groundbreaking in-vivo rat model for colorectal cancer (CRC). This new model promises to serve as a vital platform for testing new chemopreventive agents and understanding the molecular intricacies of CRC, potentially paving the way for innovative therapeutic interventions. “The development of the CRC rat model is a pioneering effort,” stated the research team, emphasizing how this advancement opens new avenues for probing into cancer mechanisms, progression, and metastasis—opportunities previously unavailable in their facilities.
The implications of this advancement extend far beyond the current research, laying a foundation for future studies that could revolutionize cancer treatment and prevention strategies. Umer Majeed Khaja, a research scholar from LPU’s Department of Zoology, led this innovative work under the guidance of Dr. Showkat Ahmad Ganie, Senior Assistant Professor at the University of Kashmir, and LPU’s Dr. Reena Singh, Associate Professor. Their research, titled “Studies on the Ameliorative Potential of Rheum Webbianum Rhizome Extracts on 1,2-Dimethylhydrazine (DMH)-Induced Colorectal Cancer and Associated Hepatic and Haematological Abnormalities in Swiss Albino Rats,” contributes significantly to the field of cancer research.
Recognized internationally, the research has been accepted for publication in Elsevier’s prestigious Journal of Ethnopharmacology. Experts have praised the study as an invaluable addition to ethnopharmacology and cancer research, citing its in-depth exploration using both in-vitro and in-vivo CRC models. Additionally, the research findings show promise regarding the chemopreventive potential of Rheum webbianum (RW) rhizome extracts. The study specifically investigates the protective effects of these extracts against DMH-induced colorectal cancer in Swiss albino rats.
The study’s findings highlight the ameliorative properties of RW rhizome extracts in countering colorectal cancer and associated liver and blood abnormalities. This suggests its potential as a natural chemopreventive agent, offering a glimmer of hope in the ongoing battle against cancer.
Umer’s work, governed by the Institutional Animal Ethics Committee guidelines, garnered support from the Department of Zoology and faculty like Prof. Fayaz Ahmad. Moreover, the research has seen substantial contributions from Dr. Chirag Chopra, Assistant Professor at LPU’s School of Bioengineering and Biosciences, underscoring a collaborative effort. Both LPU and the University of Kashmir regard this project as a pivotal step forward in the quest for innovative cancer research and treatment solutions.
This development not only showcases the potential of collaborative research projects between universities but also underscores the vital role of natural compounds in cancer prevention strategies. As the scientific community continues to uncover the depths of CRC, the insights gained from this study could inspire new directions in therapeutic approaches and establish a robust groundwork for future investigations. The research heralds a new era of hope in understanding and combating colorectal cancer, promising advancements that could reshape treatment paradigms for patients worldwide.
Original Source: https://www.tribuneindia.com/news/punjab/ivory-tower-lpu-kashmir-varsity-achieve-milestone-in-colorectal-cancer-research/
Category :
Tags:
Publish Date: 2025-04-08 04:45:00
