A study by the University of Basel has confirmed a link between poor sleep and metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease. Affecting 30% of adults and up to 14% of children, MASLD is predicted to impact over 55% of adults by 2040. Published in Frontiers in Network Physiology, the study reveals that MASLD patients have significantly fragmented sleep, waking 55% more at night and staying awake longer after first falling asleep compared to healthy individuals. Daytime sleep duration and frequency also increased in MASLD patients. The study involved 46 individuals with MASLD, MASH, or MASH with cirrhosis, compared against 24 healthy and cirrhosis-affected volunteers using actigraphs to monitor sleep patterns. Results indicated similar sleep impairments among the groups. Additionally, 32% of MASLD patients experienced sleep issues due to psychological stress, versus 6% of healthy participants. The study emphasizes sleep fragmentation’s role in MASLD development, though it’s unclear if MASLD or sleep disorders occur first. Factors like genetics, environment, and immune responses, driven by obesity and metabolic syndrome, are likely involved.
Original Source: https://www.sentinelassam.com/topheadlines/liver-disease-may-affect-your-sleep
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Publish Date: 2024-12-05 07:52:00
