A recent study by scientists from the Indian Council of Medical Research (ICMR) has identified key risk factors for breast cancer among women in India. Breast cancer ranks among the top three cancers affecting women in the country, with expected annual incidence increases of approximately 5.6%, amounting to about 50,000 new cases each year.
The research team at ICMR’s National Centre for Disease Informatics and Research (NCDIR) in Bengaluru performed a systematic review and meta-analysis of 31 studies involving 27,925 participants, 45% of whom were diagnosed with breast cancer. The findings, published in the journal Cancer Epidemiology, revealed that factors such as reproductive timing, hormonal exposure, central obesity, and family history significantly influence breast cancer risk among Indian women.
Key risks include late menopause (occurring after age 50), having a first pregnancy after age 30, marrying at an older age, undergoing multiple abortions, and central obesity, defined as a waist-to-hip ratio exceeding 85 cm. Lifestyle factors such as poor sleep quality, irregular sleep patterns, sleeping in lit rooms, and high stress levels were also linked to an increased risk. Conversely, higher levels of physical activity were associated with a reduced risk.
The analysis indicated that women over 50 face a three-fold greater risk, while those aged 35 to 50 have a 1.63-fold increased risk, underscoring the importance of early screening for women in their 40s. However, variations in age classifications across studies may contribute to inconsistencies in the results. In contrast to high-income countries, where breast cancer rates rise sharply post-50, India sees a higher incidence among women in their 40s and 50s.
Researchers led by Saravanan Vijayakumar highlighted that genetic susceptibility, earlier reproductive transitions, and unique lifestyle factors may explain this disparity. They stressed the significance of early screening programs to facilitate timely intervention.
The study also drew attention to the role of low Body Mass Index (BMI) as a potential factor influencing breast cancer prognosis and treatment outcomes. Given India’s high rates of abdominal obesity, lifestyle interventions aimed at reducing waist circumference may play a crucial role in breast cancer prevention.
Additionally, the review emphasized the urgent need for large-scale, population-based prospective cohort studies in India to refine strategies for breast cancer prevention and early detection.
Original Source: https://assamtribune.com/health-and-fitness/icmr-study-identifies-key-breast-cancer-risk-factors-among-indian-women-1601926
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Publish Date: 2025-12-20 15:44:00
